This spore-based probiotic contains 5 species of Bacillus, including indicus, subtilis, coagulans, licheniformis, and clausii. In addition to production of vitamins and antioxidants, these bacteria create the environment that facilitates colonization of the full spectrum of healthy probiotics. Given the rapidly growing body of evidence that the microbiome plays in immunity, digestion, and general health, this should be considered in virtually every treatment program. Particular conditions would include SIBO, neurological conditions, IBS and inflammatory bowel conditions such as Crohn's and ulcerative colitis, recurrent skin infections, and Candida and other types of fungal and yeast overgrowth. Given the similarities between the human and canine microbiome, this spore-based probiotic is appropriate for dogs with gastrointestinal issues as well.