This is a very comprehensive set of nutrients, including vitamins, minerals, botanicals, and glandular extracts. Proper adrenal function requires vitamin C, the B complex vitamins, zinc, and other minerals. Adrenals are also nourished and supported by other nutrients including malic acid, rhodiola, choline, citrus bioflavonoids, and glandular extracts of the adrenal and pituitary. All these and other nutrients are brought together in this formula. It is indicated for anyone under chronic stress where fatigue and even exhaustion is a dominant issue. It is not indicated for those under chronic stress who feel 'wired' and anxious.